HeDPAC is a health development platform that primarily works with like-minded governments, particularly in Africa and the Caribbean regions, to forge South-South partnerships that address pressing health challenges and achieve universal health coverage. Its initial establishment as an initiative within the Headquarters of the World Health Organisation was based on the valuable lessons harvested during the Covid 19 pandemic and its disproportionate impact on the two regions. The deep cultural, historical and political ties, including a sense of common identity and vision, and health challenges shared between the two regions, also contributed to its establishment. It was incubated at the WHO headquarters from May 2022 to December 2023 and is currently registered as a not-for-profit organisation in Barbados and Rwanda.